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Viral strategies

Microorganisms have a lot of tricks up their sleeve. From expressing more efflux pumps, to zombifying their hosts they have numerous strategies that leave us feeling "Hey, I should have thought about it"! Some viruses aid in making you more susceptible to mosquito bites: "Acetophenone is made by some Bacillus bacteria that grow on human (and mouse) skin. Normally skin produces an antimicrobial peptide that keeps Bacillus populations in check. But it turns out that when mice are infected with dengue and Zika, they don't produce as much of the antimicrobial peptide, and the Bacillus grows faster." [1] Hong Zhang, Yibin Zhu, Ziwen Liu, Yongmei Peng, Wenyu Peng, Liangqin Tong, Jinglin Wang, Qiyong Liu, Penghua Wang, Gong Cheng. A volatile from the skin microbiota of flavivirus-infected hosts promotes mosquito attractiveness . Cell , 2022; DOI: 10.1016/j.cell.2022.05.016

More variants and more items in our arsenal

A new variant of the corona virus has been out there with the common name Omicron (strain: B.1.1.529) believed to be out from South Africa. A few medical experts believe in booster doses to already vaccinated people. In a recent seminar that I attended, the CEO of a company gave this analogy where he compared the vaccination as a helmet on a rider. "Let us say a truck is driving in the opposite direction, the best way to ensure survival would be to drive rather safe to avoid its path than to wear a safer helmet." The Indian subcontinent is doing its best against the war on their invisible enemies and also their foes. Several people may have different views on this subject but this is an opinion. The government registered the use of a few more vaccines and medics onto the war-zone. A few more vaccines have been recently accepted ( continued from... ): 6. Covovax : licenced by Novavax (US) and produced by SII (Ierum Institute of India) is the 9th vaccine listed by the WH...

SARS-CoV-2 | Strains, Variants, Mutants and Recombination

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The genome of SARS-CoV-2 consists of an mRNA single strand, packed at the heart of the virus, is the primary construct for its replication. The sequence contains information necessary for constructing the viral machinery proteins by the process known as translation. Below is an image showing the several viral proteins coded by the genetic material that is present in the virus [ ref ].   The physical structure of the virus that is made by several proteins is shown in the image [ ref ]. These proteins make up the structural machinery of the protein. The remaining viral machinery are called non-structural proteins (NSP) that are necessary for functions such as polymerization, inhibition, proof reading and many other that allow the virus to infect and replicate in host organisms. The use of the terms mutants, variants and strains have become quite frequent in the news that we hear today. These phenomenon occur due to the process called recombination . Simply put, recombination i...

Science in action: Is it the end of coronavirus?

Science is the cognitive thought of a pack of beings. It will never stop being pursued even if ONE wants it to. The progression of science is to mold it into something new every day. Science is always intriguing when it is new. The coronavirus pandemic struck the global earth population like the plague in a rat's nest. Today, an year after the origin of this invisible enemy, after millions lost their life in the spike of this universal antagonist, there is a ray of hope that everyone has been eagerly waiting for. Science has paved its research into a source of global calm. Vaccines are in their final stages of approval and have already begun being administered to the global population in order to prepare the human immune system to wage the bloody war . Several preventive-cure, vaccines for the COVID pandemic have been brought to light. --- Popular vaccines in order of their approval and human administration are: 1. Sputnik V - (DNA of a SARS-CoV-2 type adenovirus)     ...

The economy can be fixed tomorrow but not the world we live in

Albeit the war on the invisible enemy rages on, it is worthwhile to rethink our economy and discuss the preservation of this home planet for the better living of our future generations. In this world where the rich become richer and the poor remain poor, there is very little concern from our fellow people about the impact of human activities on mother nature. Yes, the rich and the governments are responsible for all the bigotry within us, but let us rethink a simple relationship that strains our environment. The root cause for the surge in our impact on this environment is by overpopulation. The poor are densely populated seeking jobs that are not existent and the rich are sparsely populated determined not to share their wealth. This increases the dependence of both populations on nature to provide a better home.  Now imagine a selected small area that is so densely populated that any good change brought about here can have a large impact on most environmental problems around the g...

Balance: Part 1

The blue planet is a sustainable and suitable living space provided to all living species shielded by the balance that is being maintained by nature. For a long time, I have been poking at the subject of a balance that nature is trying to preserve. This balance is a sort of dynamic equilibrium, a consort of energies defining the philosophical capacity of any entity at a particular time. Most spiritual learnings have come to understand the belief that one reaps what they sow. Likewise, nature would treat one the same way they treat her. This helps constitute the philosophical balance.  Every member of the earth's biodiversity constitutes a balance in nature. The presence of an entity in this universe is balanced by the absence of another. Though scientifically not comprehensible yet, from our past, we humans tend to understand and observe the work of mother nature. She cares for those who need it and shelters those who don't.  With power also comes responsibility. The bala...

Nature's diplomacy

The surface area of the earth is about half a billion square kilometres. Mother nature brought humans into existence on this expanse and allowed them to co-exist with her other creations. Over the years, humans have become adept to tackle the forces of nature and have evolved into civilised beings. However, the civilisation has run its course. Time has shown that mankind is not just a substantial threat to his surroundings but to himself also. Current environmental affairs such as the flaring pandemic, climate change, biodiversity loss and others are a consequence of humans disturbing the balance that nature tries to protect. The balance by nature will be restored at any cost, even if it has to be the end of humanity as we know it, but this is obviously not something we strive for. We have been given opportunities to mend our ways and it is time to learn about our impact on the balance. The governments and leaders who lead the politically divided nations should stand united to pr...